Article
Mutational landscape in squamous cell carcinoma of the nail unit.
Experimental dermatology - 1 Jun 2022
Dika Emi, de Biase Dario, Lambertini Martina, Alessandrini Aurora Maria, Acquaviva Giorgia, De Leo Antonio, Tallini Giovanni, Ricci Costantino, Starace Michela, Misciali Cosimo, Piraccini Bianca Maria
Abstract excerpt
Squamous cell carcinoma (SCC) is the most common malignancy of the nail unit. Pathogenetic mechanisms are yet to be determined, and a deeper molecular characterization of this disease is still necessary. The aim was to obtain a molecular characterization of NU SCC samples using an NGS approach to identify the genetic drivers involved in this tumor. The presence of HPV infection was also assessed. Furthermore, the...
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