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Article

Squamousness: Next-generation sequencing reveals shared molecular features across squamous tumor types.

Cell cycle (Georgetown, Tex.) - 1 Jan 2015

Schwaederle Maria, Elkin Sheryl K, Tomson Brett N, Carter Jennifer Levin, Kurzrock Razelle

Abstract excerpt

In order to gain a better understanding of the underlying biology of squamous cell carcinoma (SCC), we tested the hypothesis that SCC originating from different organs may possess common molecular alterations. SCC samples (N = 361) were examined using clinical-grade targeted next-generation sequencing (NGS). The most frequent SCC tumor types were head and neck, lung, cutaneous, gastrointestinal and gynecologic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26030731
DOI: 10.1080/15384101.2015.1053669
PMCID: PMC4613537

Genes

CCND1
SOX2
KRAS
NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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