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Genetic characteristics of advanced oral tongue squamous cell carcinoma in young patients

29 Jun 2023

Abstract excerpt

OBJECTIVES: We aimed to investigate genetic alterations in oral tongue squamous cell carcinoma (OTSCC) based on age and the clinical significance of these alterations in young OTSCC patients. MATERIALS AND METHODS: We detected genetic alterations in 44 cases of advanced OTSCC through next-generation sequencing and analyzed and compared patients either younger or older than 45 years. Further analysis was conducted...

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PMID: 37393663
DOI: 10.1016/j.oraloncology.2023.106466

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