Article
Molecular characterisation in tongue squamous cell carcinoma reveals key variants potentially linked to clinical outcomes.
Cancer biomarkers : section A of Disease markers - 1 Jan 2020
Alsofyani Abeer A, Dallol Ashraf, Farraj Suha A, Alsiary Rawiah A, Samkari Alaa, Alhaj-Hussain Baraa T, Khan Jalaluddin Azam, Al-Maghrabi Jaudah, Al-Khayyat Shadi S, Alkhatabi Heba, Elaimi Aisha, Buhmeida Abdelbaset, Johargy Ayman Khalid, Abuzenadah Adel M, Azhar Esam I, Al-Qahtani Mohammed H
Abstract excerpt
BACKGROUND: Oral tongue squamous cell carcinoma (OTSCC) is a highly aggressive malignancy characterized by frequent recurrence, poor survival with relatively few therapeutic options due to the late diagnosis in many cases. OBJECTIVES: Understanding the molecular pathways underlying OTSCC tumourigenesis and the discovery of diagnostic and/or prognostic biomarkers. METHODS: We performed high-throughput mutational...
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