Polymorphisms in ERBB4 and TACR1 associated with dry mouth in clozapine-treated patients.

doi:10.1017/neu.2024.9

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Article

Polymorphisms in ERBB4 and TACR1 associated with dry mouth in clozapine-treated patients.

Acta neuropsychiatrica - 1 Aug 2024

Puolakka Hanna, Solismaa Anssi, Lyytikäinen Leo-Pekka, Viikki Merja, Seppälä Niko, Mononen Nina, Lehtimäki Terho, Kampman Olli

Abstract excerpt

BACKGROUND: Sialorrhea is a common and uncomfortable adverse effect of clozapine, and its severity varies between patients. The aim of the study was to select broadly genes related to the regulation of salivation and study associations between sialorrhea and dry mouth and polymorphisms in the selected genes. METHODS: The study population consists of 237 clozapine-treated patients, of which 172 were genotyped....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38634369
DOI: 10.1017/neu.2024.9

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