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Genetic risk of clozapine-induced leukopenia and neutropenia: a genome-wide association study

3 Jun 2021

Abstract excerpt

Abstract Background Clozapine is considered to be the most effective antipsychotic medication for schizophrenia. However, it is associated with several adverse effects such as leukopenia, and the underlying mechanism has not yet been fully elucidated. The authors performed a genome-wide association study (GWAS) in a Chinese population to identify genetic markers for clozapine-induced leukopenia (CIL) and...

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PMID: 34083506
DOI: 10.1038/s41398-021-01470-z

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