Article

Adult human brain tissue cultures to study neuroHIV

2024-04-19

Abstract excerpt

HIV-associated neurocognitive disorders (HAND) persist under antiretroviral therapy as a complex pathology that has been difficult to study in cellular and animal models. Therefore, we generated an ex vivo human brain slice model of HIV-1 infection from surgically resected adult brain tissue. Brain slice cultures processed for flow cytometry showed >90% viability of dissoci-ated cells within the first three wee...

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Literature Corpus work: d34ff6f9-e439-565c-b3dc-51c5b4d43bef
DOI: 10.20944/preprints202404.1300.v1

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