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Article

Heritability of complex traits in sub-populations experiencing bottlenecks and growth.

Journal of human genetics - 1 Jul 2024

Taylor Cameron S, Lawson Daniel J

Abstract excerpt

Populations that have experienced a bottleneck are regularly used in Genome Wide Association Studies (GWAS) to investigate variants associated with complex traits. It is generally understood that these isolated sub-populations may experience high frequency of otherwise rare variants with large effect size, and therefore provide a unique opportunity to study said trait. However, the demographic history of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Multifactorial Inheritance

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait, Heritable

Share to Selection, Genetic

Source

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Identifiers

PMID: 38589509
DOI: 10.1038/s10038-024-01249-2
PMCID: PMC11199143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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