Article
Haplotype-resolved assembly of auto-polyploid genomes via combining Hi-C and gametic data.
Scientific reports - 3 Apr 2024
Zhang Xiaohui, Li Dongxi, Pan Weihua
Abstract excerpt
Haplotype-resolved genome assembly plays a crucial role in understanding allele-specific functions. However, obtaining haplotype-resolved assembly for auto-polyploid genomes remains challenging. Existing methods can be classified into reference-based phasing, assembly-based phasing, and gamete binning. Nevertheless, there is a lack of cost-effective and efficient methods for haplotyping auto-polyploid genomes. In...
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