Article
Chromosome-level scaffolding of haplotype-resolved assemblies using Hi-C data without reference genomes.
Nature plants - 1 Aug 2024
Zeng Xiaofei, Yi Zili, Zhang Xingtan, Du Yuhui, Li Yu, Zhou Zhiqing, Chen Sijie, Zhao Huijie, Yang Sai, Wang Yibin, Chen Guoan
Abstract excerpt
Scaffolding is crucial for constructing most chromosome-level genomes. The high-throughput chromatin conformation capture (Hi-C) technology has become the primary scaffolding strategy due to its convenience and cost-effectiveness. As sequencing technologies and assembly algorithms advance, constructing haplotype-resolved genomes is increasingly preferred because haplotypes can provide additional genetic...
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