Article
Assembly of whole-chromosome pseudomolecules for polyploid plant genomes using outbred mapping populations.
Nature genetics - 1 Nov 2020
Zhou Chenxi, Olukolu Bode, Gemenet Dorcus C, Wu Shan, Gruneberg Wolfgang, Cao Minh Duc, Fei Zhangjun, Zeng Zhao-Bang, George Andrew W, Khan Awais, Yencho G Craig, Coin Lachlan J M
Abstract excerpt
Despite advances in sequencing technologies, assembly of complex plant genomes remains elusive due to polyploidy and high repeat content. Here we report PolyGembler for grouping and ordering contigs into pseudomolecules by genetic linkage analysis. Our approach also provides an accurate method with which to detect and fix assembly errors. Using simulated data, we demonstrate that our approach is of high accuracy...
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