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Article

Metabolic profiling of smoking, associations with type 2 diabetes and interaction with genetic susceptibility.

European journal of epidemiology - 1 Jun 2024

Wei Yuxia, Hägg Sara, Mak Jonathan K L, Tuomi Tiinamaija, Zhan Yiqiang, Carlsson Sofia

Abstract excerpt

BACKGROUND: Smokers are at increased risk of type 2 diabetes (T2D), but the underlying mechanisms are unclear. We investigated if the smoking-T2D association is mediated by alterations in the metabolome and assessed potential interaction with genetic susceptibility to diabetes or insulin resistance. METHODS: In UK Biobank (n = 93,722), cross-sectional analyses identified 208 metabolites associated with smoking,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38555549
DOI: 10.1007/s10654-024-01117-5
PMCID: PMC11249521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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