Article
Metabotype identification via fasting and postprandial metabolomics and its association with type 2 diabetes incidence.
Cardiovascular diabetology - 8 Jul 2025
Deng Keyong, Hughes David A, de Mutsert Renée, van Hylckama Vlieg Astrid, le Cessie Saskia, Rosendaal Frits R, Mook-Kanamori Dennis O, van Dijk Ko Willems, Timpson Nicholas J, Li-Gao Ruifang
Abstract excerpt
BACKGROUND: Metabotypes represent distinct metabolic profiles that groups of individuals share, facilitating disease risk stratification. We aimed to apply metabolomics to identify metabotypes in different prandial states and examine its associations with type 2 diabetes mellitus (T2DM) risk. METHODS: Using fasting and postprandial metabolomic data from the Netherlands Epidemiology of Obesity (NEO) study...
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