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Article

SRC-3 Has a Role in Cancer Other Than as a Nuclear Receptor Coactivator

1 Jan 2011

Abstract excerpt

Steroid receptor coactivator-3 (SRC-3), also known as AIB1, is a member of the p160 steroid receptor coactivator family. Since SRC-3 was found to be amplified in breast cancer in 1997, the role of SRC-3 in cancer has been broadly investigated. SRC-3 initially was identified as a transcriptional coactivator for nuclear receptors such as the estrogen receptor (ER), involved in the proliferation of hormone-dependent...

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PMID: 21647249
DOI: 10.7150/ijbs.7.664

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