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Nuclear Receptor Coactivator 2 Promotes Human Breast Cancer Cell Growth by Positively Regulating the MAPK/ERK Pathway

19 Mar 2019

Abstract excerpt

As a member of the p160 steroid receptor coactivator (SRC) gene family, nuclear receptor coactivator 2 (NCOA2) is known to play essential roles in many physiological and pathological processes, including development, endocrine regulation and tumorigenesis. However, the biological functions of NCOA2 in breast cancer is not fully understood. We found that the copy number of NCOA2 gene was frequently amplified in...

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PMID: 30941313
DOI: 10.3389/fonc.2019.00164

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