Article
The role of steroid receptor coactivator-3 (SRC-3) in human malignant disease.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Mar 2010
Gojis O, Rudraraju B, Alifrangis C, Krell J, Libalova P, Palmieri C
Abstract excerpt
BACKGROUND: The p160 steroid receptor coactivator (SRC) family is critical to the transcriptional activation function of nuclear hormone receptors. A key member of this family is SRC-3, initially found to be amplified and expressed in breast cancer it has subsequent been shown to be expressed in malignant disease arising from a wide range of other organs. An understanding of the potential role of SRC-3 in the...
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