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Article

Steroid receptor coactivator-3 as a potential molecular target for cancer therapy

27 Aug 2012

Abstract excerpt

INTRODUCTION: Steroid receptor coactivator-3 (SRC-3), also called amplified-in-breast cancer-1 (AIB1), is an oncogenic coactivator in endocrine and non-endocrine cancers. Functional studies demonstrate SRC-3 promotes numerous aspects of cancer, through its capacity as a coactivator for nuclear hormone receptors and other transcription factors, and via its ability to control multiple growth pathways...

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Share to Estrogen and related hormone effects
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22924430
DOI: 10.1517/14728222.2012.718330

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