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Article

SRC: Regulation, Role in Human Carcinogenesis and Pharmacological Inhibitors

1 Jun 2004

Abstract excerpt

The cellular signaling machinery is a complex network of cross-talking proteins that enables dynamic communication between upstream causal factors and downstream effectors. Non-receptor tyrosine kinases, including Src, are the intermediates of signal transfer, controlling pathways as diverse as cell growth, death, differentiation, migration, and genome maintenance. When expressed as viral genes these proteins are...

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PMID: 15180537
DOI: 10.2174/1381612043384457

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