Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The β2-adrenergic receptor associates with CXCR4 multimers in human cancer cells

28 Mar 2024

Abstract excerpt

While the existence and functional role of class C G-protein-coupled receptors (GPCR) dimers is well established, there is still a lack of consensus regarding class A and B GPCR multimerization. This lack of consensus is largely due to the inherent challenges of demonstrating the presence of multimeric receptor complexes in a physiologically relevant cellular context. The C-X-C motif chemokine receptor 4 (CXCR4)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokine receptors and signaling
Share to Neuropeptides and Animal Physiology
Share to Receptor Mechanisms and Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38547061
DOI: 10.1073/pnas.2304897121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The β2-adrenergic receptor associates with CXCR4 multimers in human cancer cellsPMID 38547061Read ↗

Multiple mechanisms of self-association of chemokine receptors CXCR4 and CCR5 demonstrated by deep mutagenesis.Semantic proximity Read ↗

Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists.Semantic proximity Read ↗

FLIM-FRET-Based Structural Characterization of a Class-A GPCR Dimer in the Cell Membrane.Semantic proximity Read ↗

A novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transfer.Semantic proximity Read ↗

Serotonin type 4 receptor dimers.Semantic proximity Read ↗

Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the Protean Effects of “Selective” AntagonistsSemantic proximity Read ↗

Class A Plexins Are Organized as Preformed Inactive Dimers on the Cell Surface.Semantic proximity Read ↗

CXCR7 Controls Competition for Recruitment of β-Arrestin 2 in Cells Expressing Both CXCR4 and CXCR7Semantic proximity Read ↗

Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function.Semantic proximity Read ↗

Fluorescence cross-correlation spectroscopy quantifies affinity, cooperativity, and kinetic stability in ternary protein complexesSemantic proximity Read ↗

A G protein-coupled receptor dimer imaging assay reveals selectively modified pharmacology of neuropeptide Y Y1/Y5 receptor heterodimers.Semantic proximity Read ↗

Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.