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The Role of DNA Repair (XPC, XPD, XPF, and XPG) Gene Polymorphisms in the Development of Myeloproliferative Neoplasms.

Medicina (Kaunas, Lithuania) - 19 Mar 2024

Crișan Adriana-Stela, Tripon Florin, Bogliș Alina, Crauciuc George-Andrei, Trifa Adrian P, Lázár Erzsébet, Macarie Ioan, Gabor Manuela Rozalia, Bănescu Claudia

Abstract excerpt

Background and Objectives: Several polymorphisms have been described in various DNA repair genes. Nucleotide excision DNA repair (NER) detects defects of DNA molecules and corrects them to restore genome integrity. We hypothesized that the XPC, XPD, XPF, and XPG gene polymorphisms influence the appearance of myeloproliferative neoplasms (MPNs). Materials and Methods: We investigated the XPC 1496C>T (rs2228000,...

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Identifiers

PMID: 38541232
DOI: 10.3390/medicina60030506
PMCID: PMC10972134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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