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Article

Polymorphisms in nucleotide excision repair genes and susceptibility to colorectal cancer in the Polish population.

Molecular biology reports - 1 Mar 2015

Paszkowska-Szczur Katarzyna, Scott Rodney J, Górski Bohdan, Cybulski Cezary, Kurzawski Grzegorz, Dymerska Dagmara, Gupta Satish, van de Wetering Thierry, Masojć Bartłomiej, Kashyap Aniruddh, Gapska Paulina, Gromowski Tomasz, Kładny Józef, Lubiński Jan, Dębniak Tadeusz

Abstract excerpt

Xeroderma pigmentosum (XP) is a rare autosomal recessive disease that is associated with a severe deficiency in nucleotide excision repair. Genetic polymorphisms in XP genes may be associated with a change in DNA repair capacity, which could be associated with colorectal cancer development. We assessed the association between 94 single nucleotide polymorphisms (SNPs) within seven XP genes (XPA-XPG) and the...

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Identifiers

PMID: 25391773
DOI: 10.1007/s11033-014-3824-z
PMCID: PMC4330403

Genes

XPC
XPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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