Association of DNA repair gene XPC Ala499Val (rs2228000 C>T) and Lys939Gln (rs2228001 A>C) polymorphisms with the risk of chronic myeloid leukemia: A case-control study in a South Indian population.

doi:10.1002/jgm.3339

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association of DNA repair gene XPC Ala499Val (rs2228000 C>T) and Lys939Gln (rs2228001 A>C) polymorphisms with the risk of chronic myeloid leukemia: A case-control study in a South Indian population.

The journal of gene medicine - 1 Jul 2021

Lakkireddy Samyuktha, Aula Sangeetha, Kapley Atya, Gundeti Sadashivudu, Kutala Vijay Kumar, Jamil Kaiser

Abstract excerpt

BACKGROUND: Xeroderma pigmentosum complementation group C (XPC), a DNA repair protein, plays an important role in the maintenance of genomic integrity and is essential for the nucleotide excision repair pathway. Polymorphisms in the XPC gene may alter DNA repair leading to genetic instability and oncogenesis. The present study aimed to assess the relationship between the XPC Ala499Val (rs2228000 C>T) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to DNA-Binding Proteins

Share to Genotyping Techniques

Share to Haplotypes

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Odds Ratio

Share to Prognosis

Source

Open in PubMed

Identifiers

PMID: 33829606
DOI: 10.1002/jgm.3339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of DNA repair gene XPC Ala499Val (rs2228000 C>T) and Lys939Gln (rs2228001 A>C) polymorphisms with the risk of chronic myeloid leukemia: A case-control study in a South Indian population.PMID 33829606Read ↗

Associations of Lys939Gln and Ala499Val polymorphisms of the XPC gene with cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

Polymorphism of XRCC1, XRCC3, and XPD genes and risk of chronic myeloid leukemia.Semantic proximity Read ↗

Polymorphisms in XPC, XPD and XPG DNA repair genes and leukemia risk in a Tunisian population.Semantic proximity Read ↗

XPC genetic polymorphisms correlate with the response to imatinib treatment in patients with chronic phase chronic myeloid leukemia.Semantic proximity Read ↗

DNA repair gene variants are associated with an increased risk of myelodysplastic syndromes in a Czech population.Semantic proximity Read ↗

The association between XPC Lys939Gln gene polymorphism and urinary bladder cancer susceptibility: a systematic review and meta-analysis.Semantic proximity Read ↗

Polymorphisms in the XPC gene affect urinary bladder cancer risk: a case-control study, meta-analyses and trial sequential analyses.Semantic proximity Read ↗

Association of XPC Polymorphisms with Cutaneous Malignant Melanoma Risk: Evidence from a Meta-Analysis.Semantic proximity Read ↗

Concurrent effects of ABCB1 C3435T, ABCG2 C421A, and XRCC1 Arg194Trp genetic polymorphisms with risk of cancer, clinical output, and response to treatment with imatinib mesylate in patients with chronic myeloid leukemia.Semantic proximity Read ↗

DNA repair genes XPC, XPG polymorphisms: relation to the risk of colorectal carcinoma and therapeutic outcome with Oxaliplatin-based adjuvant chemotherapy.Semantic proximity Read ↗

Associations between XPC polymorphisms and risk of cancers: A meta-analysis.Semantic proximity Read ↗

Genotypes, haplotypes and diplotypes of XPC and risk of bladder cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.