Article
Investigation of DNA repair gene variants on myelodysplastic syndromes in a Turkish population.
Medical oncology (Northwood, London, England) - 1 Oct 2014
Aktuglu Mehmet Burak, Ayer Mesut, Bireller Elif S, Rencuzogullari Cagla, Acik Hasan, Karaali Zeynep, Alioglu Taner, Yigit Namik, Velet Mustafa, Atalay Eray, Ure Oznur Sari, Cakmakoglu Bedia
Abstract excerpt
The aim of this study was to assess the possible influence of genetic polymorphisms in hOGG1, XRCC1, XRCC3, XPD, XPG and APE1 on the observed DNA damage in a group of Turkish myelodysplastic syndrome (MDS) patients. A total of 39 patients with myelodysplastic syndrome and 78 age-matched healthy control subjects were included in our study. Polymerase chain reaction/restriction fragment length polymorphism analysis...
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