Article
Immune interface interference vaccines: An evolution‐informed approach to anti‐bacterial vaccine design
1 Mar 2024
Abstract excerpt
Developing protein-based vaccines against bacteria has proved much more challenging than producing similar immunisations against viruses. Currently, anti-bacterial vaccines are designed using methods based on reverse vaccinology. These identify broadly conserved, immunogenic proteins using a combination of genomic and high-throughput laboratory data. While this approach has successfully generated multiple...
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