Article

Rationally designed minimized TbpB confers broad protection against meningococcal infection

2025-10-31

Abstract excerpt

Transferrin binding protein B (TbpB), an iron acquisition protein, has long been recognized as a promising vaccine candidate targeting the pathogenic Neisseria species, including Neisseria meningitidis , the cause of meningococcal disease, and Neisseria gonorrhoeae , the cause of gonorrhea. A challenge to the development of this protein as a vaccine immunogen is the extent of antigenic variability it exhibits, w...

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Literature Corpus work: 2bb8974d-6624-5271-ab5d-aa9bdedab98a
DOI: 10.1101/2025.10.30.685603

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