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Article

Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes

21 Feb 2018

Abstract excerpt

4CMenB is the first broad coverage vaccine for the prevention of invasive meningococcal disease caused by serogroup B strains. To gain a comprehensive picture of the antibody response induced upon 4CMenB vaccination and to obtain relevant translational information directly from human studies, we have isolated a panel of human monoclonal antibodies from adult vaccinees. Based on the Ig-gene sequence of the...

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PMID: 29487324
DOI: 10.1038/s41598-018-22057-7

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