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Neisseria meningitidis factor H-binding protein fHbp: a key virulence factor and vaccine antigen

23 Feb 2015

Abstract excerpt

Neisseria meningitidis is a leading cause of meningitis and sepsis worldwide. The first broad-spectrum multicomponent vaccine against serogroup B meningococcus (MenB), 4CMenB (Bexsero(®)), was approved by the EMA in 2013, for prevention of MenB disease in all age groups, and by the US FDA in January 2015 for use in adolescents. A second protein-based MenB vaccine has also been approved in the USA for adolescents...

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PMID: 25704037
DOI: 10.1586/14760584.2015.1016915

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