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CD44-Mediated Poor Prognosis in Glioma Is Associated With M2-Polarization of Tumor-Associated Macrophages and Immunosuppression

3 Feb 2022

Abstract excerpt

Background Glioma is the most common primary brain tumor with a poor prognosis. Key genes that are negatively related to prognosis may provide the therapy targets to cure glioma. To clarify the role of CD44 in glioma, we explored its function at bulk-transcriptome, spatial and single-cell transcriptome levels. Methods In total, expression profiles with survival data of whole-grade glioma from The Cancer Genome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35187044
DOI: 10.3389/fsurg.2021.775194

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