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Article

Diverse Macrophages Constituted the Glioma Microenvironment and Influenced by PTEN Status

21 Feb 2022

Abstract excerpt

The glioma immune microenvironment (GIM), consisting of glioma cells, stromal cells, and immune cells, accelerates the initiation, development, immune evasion, chemoresistance, and radioresistance of glioblastoma (GBM), whereas the immunosuppressive mechanisms of GBM have not been thoroughly elucidated to date. The glioma data downloaded from The Cancer Genome Atlas (TCGA) and the Chinese Glioma Genome Atlas...

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PMID: 35265085
DOI: 10.3389/fimmu.2022.841404

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