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SPP1 as a Prognostic and Immunotherapeutic Biomarker in Gliomas and Other Cancer Types: A Pan-Cancer Study

1 Feb 2025

Abstract excerpt

Background: Gliomas, including glioblastoma (GBM), present significant treatment challenges due to their poor prognosis and complex tumor microenvironment. This study investigates the role of Secreted Phosphoprotein 1 (SPP1) as a prognostic and immunotherapeutic biomarker in gliomas and other cancers through pan-cancer analysis. Methods: A comprehensive pan-cancer analysis was conducted using datasets from UCSC...

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PMID: 39963684
DOI: 10.2147/jir.s505237

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