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Article

A Novel DNA Variant in SMARCA4 Gene Found in a Patient Affected by Early Onset Colon Cancer.

International journal of molecular sciences - 27 Feb 2024

Di Maggio Federica, Boccia Giuseppe, Nunziato Marcella, Filotico Marcello, Montesarchio Vincenzo, D'Armiento Maria, Corcione Francesco, Salvatore Francesco

Abstract excerpt

Colorectal cancer is the third leading cause of death from neoplasia worldwide. Thanks to new screening programs, we are now seeing an increase in Early Onset of ColoRectal Cancer (EOCRC) in patients below the age of 50. Herein, we report a clinical case of a woman affected by EOCRC. This case illustrates the importance of genetic predisposition testing also in tumor patients. Indeed, for our patient, we used a...

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Identifiers

PMID: 38473962
DOI: 10.3390/ijms25052716
PMCID: PMC10932324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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