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A Transcriptome and Methylome Study Comparing Tissues of Early and Late Onset Colorectal Carcinoma

17 Nov 2022

Abstract excerpt

There is an increase in the incidence of early onset colorectal carcinoma (EOCRC). To better understand if there is any difference in molecular pathogenesis of EOCRC and late onset colorectal carcinoma (LOCRC), we compared the clinical, histological, transcriptome, and methylome profile of paired CRC and healthy colonic tissue from 67 EOCRC and 98 LOCRC patients. The frequency of stage 3 CRC, lymph node...

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PMID: 36430738
DOI: 10.3390/ijms232214261

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