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Article

First-decade patient with colorectal cancer carrying both germline and somatic mutations in APC gene.

BMC cancer - 14 Dec 2017

Yeh Yung-Sung, Chang Yu-Tang, Ma Cheng-Jen, Huang Ching-Wen, Tsai Hsiang-Lin, Chen Yi-Ting, Wang Jaw-Yuan

Abstract excerpt

BACKGROUND: Colorectal carcinoma (CRC) is one of the most common causes of cancer-related deaths. The mean age of patients with CRC ranges from 49 to 60 years. Pediatric CRC is unusual, which often escapes early diagnosis because of a lack of awareness of its occurrence in children. The association between the mutation of APC and the occurrence of CRC in the first decade of life remains unknown. CASE...

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Source

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Identifiers

PMID: 29237421
DOI: 10.1186/s12885-017-3878-0
PMCID: PMC5729288

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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