Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA repair capacity and response to treatment of colon cancer.

Pharmacogenomics - 1 Nov 2019

Vodicka Pavel, Vodenkova Sona, Buchler Tomas, Vodickova Ludmila

Abstract excerpt

DNA repair, a complex biological process, ensures genomic integrity. Alterations in DNA repair, occurring in many cancers, contribute to the accumulation of mutations in the genome, resulting in genomic instability and cancer progression. DNA repair also plays a substantial role in response to chemotherapeutics: rapidly dividing colon cancer cells, vulnerable to DNA-damaging agents and overcoming DNA repair,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Death
Share to Colonic Neoplasms
Share to DNA Damage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to Epigenesis, Genetic

Share to Gene Expression Regulation, Neoplastic

Share to Genomic Instability

Share to Prognosis

Source

Identifiers

PMID: 31691643
DOI: 10.2217/pgs-2019-0070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA repair capacity and response to treatment of colon cancer.PMID 31691643Read ↗

DNA repair mechanisms in colorectal carcinogenesis.Semantic proximity Read ↗

DNA repair defects in colon cancerSemantic proximity Read ↗

Association of DNA repair gene polymorphisms with colorectal cancer risk and treatment outcomes.Semantic proximity Read ↗

Mismatch Repair and Colon Cancer: Mechanisms and Therapies Explored.Semantic proximity Read ↗

DNA mismatch repair and colorectal cancer.Semantic proximity Read ↗

Genetics of hereditary colon cancer.Semantic proximity Read ↗

Molecular Aspects of Colorectal Adenomas: The Interplay among Microenvironment, Oxidative Stress, and Predisposition.Semantic proximity Read ↗

Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases in Colorectal Cancer PatientsSemantic proximity Read ↗

Personalized colon cancer care in 2010.Semantic proximity Read ↗

DNA mismatch repair and colon cancer.Semantic proximity Read ↗

Exploiting DNA repair defects in colorectal cancerSemantic proximity Read ↗

Nucleotide excision repair and response and survival to chemotherapy in colorectal cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.