Article
Approach to early-onset colorectal cancer: clinicopathological, familial, molecular and immunohistochemical characteristics.
World journal of gastroenterology - 7 Aug 2010
Perea Jose, Alvaro Edurne, Rodríguez Yolanda, Gravalos Cristina, Sánchez-Tomé Eva, Rivera Barbara, Colina Francisco, Carbonell Pablo, González-Sarmiento Rogelio, Hidalgo Manuel, Urioste Miguel
Abstract excerpt
AIM: To characterize clinicopathological and familial features of early-onset colorectal cancer (CRC) and compare features of tumors with and without microsatellite instability (MSI). METHODS: Forty-five patients with CRC aged 45 or younger were included in the study. Clinical information, a three-generation family history, and tumor samples were obtained. MSI status was analyzed and mismatch repair genes were...
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