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Article

A mutational comparison of adult and adolescent and young adult (AYA) colon cancer.

Cancer - 1 Mar 2018

Tricoli James V, Boardman Lisa A, Patidar Rajesh, Sindiri Sivasish, Jang Jin S, Walsh William D, McGregor Paul M, Camalier Corinne E, Mehaffey Michele G, Furman Wayne L, Bahrami Armita, Williams P Mickey, Lih Chih-Jian, Conley Barbara A, Khan Javed

Abstract excerpt

BACKGROUND: It is possible that the relative lack of progress in treatment outcomes among adolescent and young adult (AYA) patients with cancer is caused by a difference in disease biology compared with the corresponding diseases in younger and older individuals. There is evidence that colon cancer is more aggressive and has a poorer prognosis in AYA patients than in older adult patients. METHODS: To further...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29194591
DOI: 10.1002/cncr.31136
PMCID: PMC5821537

Genes

BRCA2
MYCBP2
ATM
ATR
CTNND1
KIT
MCPH1
MYC
PTCH1
PTEN
RASGRP3
ROBO1
TOPORS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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