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CRISPRi-Driven Genetic Screening for Designing Novel Microbial Phenotypes.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024

Kang Minjeong, Kim Kangsan, Cho Byung-Kwan

Abstract excerpt

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 system has enabled rapid advances in genomic engineering and transcriptional regulation. Specifically, CRISPR interference (CRISPRi) system has been used to systematically investigate the gene functions of microbial strains in a high-throughput manner. This method involves growth profiling using cells that have been transformed with the...

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PMID: 38468085
DOI: 10.1007/978-1-0716-3658-9_7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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