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Multivariate canonical correlation analysis identifies additional genetic variants for chronic kidney disease

9 Mar 2024

Abstract excerpt

Chronic kidney diseases (CKD) have genetic associations with kidney function. Univariate genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with estimated glomerular filtration rate (eGFR) and blood urea nitrogen (BUN), two complementary kidney function markers. However, it is unknown whether additional SNPs for kidney function can be identified by...

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PMID: 38459044
DOI: 10.1038/s41540-024-00350-8

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