Article
A clustering approach to improve our understanding of the genetic and phenotypic complexity of chronic kidney disease
2023-10-16
Abstract excerpt
<title>Abstract</title> <p>Chronic kidney disease (CKD) is a complex disorder that causes a gradual loss of kidney function, affecting approximately 9.1% of the world's population. Here, we use a soft-clustering algorithm to deconstruct its genetic heterogeneity. First, we selected 322 CKD-associated independent genetic variants from published genome-wide association studies (GWAS) and added association results f...
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Identifiers and source
- Literature Corpus work
- 13a9436f-3354-5efd-a7db-e683c94f027d
- DOI
- 10.21203/rs.3.rs-3424565/v1