Article
Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.
PLoS genetics - 1 Sept 2011
Liu Ching-Ti, Garnaas Maija K, Tin Adrienne, Kottgen Anna, Franceschini Nora, Peralta Carmen A, de Boer Ian H, Lu Xiaoning, Atkinson Elizabeth, Ding Jingzhong, Nalls Michael, Shriner Daniel, Coresh Josef, Kutlar Abdullah, Bibbins-Domingo Kirsten, Siscovick David, Akylbekova Ermeg, Wyatt Sharon, Astor Brad, Mychaleckjy Josef, Li Man, Reilly Muredach P, Townsend Raymond R, Adeyemo Adebowale, Zonderman Alan B, de Andrade Mariza, Turner Stephen T, Mosley Thomas H, Harris Tamara B, Rotimi Charles N, Liu Yongmei, Kardia Sharon L R, Evans Michele K, Shlipak Michael G, Kramer Holly, Flessner Michael F, Dreisbach Albert W, Goessling Wolfram, Cupples L Adrienne, Kao W Linda, Fox Caroline S
Abstract excerpt
Chronic kidney disease (CKD) is an increasing global public health concern, particularly among populations of African ancestry. We performed an interrogation of known renal loci, genome-wide association (GWA), and IBC candidate-gene SNP association analyses in African Americans from the CARe Renal Consortium. In up to 8,110 participants, we performed meta-analyses of GWA and IBC array data for estimated...
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