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Article

Comprehensive Inherited Risk Estimation for Risk-Based Breast Cancer Screening in Women.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 May 2024

Mars Nina, Kerminen Sini, Tamlander Max, Pirinen Matti, Jakkula Eveliina, Aaltonen Kirsimari, Meretoja Tuomo, Heinävaara Sirpa, Widén Elisabeth, Ripatti Samuli

Abstract excerpt

PURPOSE: Family history (FH) and pathogenic variants (PVs) are used for guiding risk surveillance in selected high-risk women but little is known about their impact for breast cancer screening on population level. In addition, polygenic risk scores (PRSs) have been shown to efficiently stratify breast cancer risk through combining information about common genetic factors into one measure. METHODS: In longitudinal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38422475
DOI: 10.1200/JCO.23.00295
PMCID: PMC11095905

Genes

FH
CHEK2
PALB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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