Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Organ Specificity and Heterogeneity of Cancer-Associated Fibroblasts in Colorectal Cancer

11 Oct 2021

Abstract excerpt

Fibroblasts constitute a ubiquitous mesenchymal cell type and produce the extracellular matrix (ECM) of connective tissue, thereby providing the structural basis of various organs. Fibroblasts display differential transcriptional patterns unique to the organ of their origin and they can be activated by common stimuli such as transforming growth factor-β (TGF-β) and platelet-derived growth factor (PDGF) signaling....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer, Hypoxia, and Metabolism
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34681633
DOI: 10.3390/ijms222010973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Organ Specificity and Heterogeneity of Cancer-Associated Fibroblasts in Colorectal CancerPMID 34681633Read ↗

Fibroblasts in Orchestrating Colorectal Tumorigenesis and ProgressionSemantic proximity Read ↗

Diversity and Biology of Cancer-Associated FibroblastsSemantic proximity Read ↗

The Origin, Differentiation, and Functions of Cancer-Associated Fibroblasts in Gastrointestinal CancerSemantic proximity Read ↗

Heterogeneity, crosstalk, and targeting of cancer-associated fibroblasts in cholangiocarcinomaSemantic proximity Read ↗

Cancer associated fibroblasts (CAFs) in tumor microenvironmentSemantic proximity Read ↗

Recent advances in cancer-associated fibroblast: Biomarkers, signaling pathways, and therapeutic opportunities.Semantic proximity Read ↗

Cancer-associated Fibroblasts: Origins, Heterogeneity and Functions in Tumor MicroenvironmentSemantic proximity Read ↗

The Impact of Cancer-Associated Fibroblasts on the Biology and Progression of Colorectal CarcinomasSemantic proximity Read ↗

Cancer-Associated Fibroblast Heterogeneity: A Factor That Cannot Be Ignored in Immune Microenvironment RemodelingSemantic proximity Read ↗

The roles of tumor- and metastasis-promoting carcinoma-associated fibroblasts in human carcinomas.Semantic proximity Read ↗

Cancer-associated fibroblasts: heterogeneity and their role in the tumor immune responseSemantic proximity Read ↗

Fibroblasts—a key host cell type in tumor initiation, progression, and metastasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.