Article
Association between antihypertensive drugs and hepatocellular carcinoma: A trans-ancestry and drug-target Mendelian randomization study.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jun 2023
Wang Zhenqian, Lu Jiawen, Hu Jingyi
Abstract excerpt
BACKGROUND AND AIMS: Antihypertensive drugs were recently reported to have an oncogenic role in common cancer, however, whether these drugs would affect the risk of hepatocellular carcinoma (HCC) remains unclear. METHODS: A drug-target Mendelian randomization method was adopted to examine the long-term effect of 12 antihypertensive drugs classes on the risk of HCC in Europeans and East Asians. To proxy...
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