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Article

The causal association between systolic blood pressure and breast cancer: a two sample Mendelian randomization study.

BMC cancer - 22 Jan 2026

Awada Zainab, Kazmi Nabila, Jones Hannah J, Lewis Sarah J

Abstract excerpt

BACKGROUND: Breast cancer (BC) is the leading cause of cancer incidence worldwide. Observational studies have suggested that hypertension may be a risk factor for BC. We tested whether systolic blood pressure (SBP) may influence BC and BC subtypes using a Mendelian randomisation (MR) approach. METHODS: We used 334 genetic variants associated with SBP as an instrumental variable. Effect estimates were obtained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41572223
DOI: 10.1186/s12885-025-15513-x
PMCID: PMC12914972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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