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Causal plasma metabolites for breast cancer risk: a two-sample Mendelian randomization study with colocalization evidence

2025-05-09

Abstract excerpt

<title>Abstract</title> <p>Background This study aimed to estimate causal effects of 1,400 human plasma metabolites on breast cancer (BC) risk using a two-sample Mendelian randomization (MR) framework. Methods We employed a two-sample Mendelian randomization framework to investigate causal associations between plasma metabolites and BC risk. We applied strict quality control with Bonferroni correction and condu...

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Literature Corpus work
431ddbfb-9c69-5f73-876d-c1711272e0e7
DOI
10.21203/rs.3.rs-6417186/v1
Open publication

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Causal plasma metabolites for breast cancer risk: a two-sample Mendelian randomization study with colocalization evidenceDOI 10.21203/rs.3.rs-6417186/v1
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