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Article

Many faces, many places: delving deeper into CAF heterogeneity in NSCLC.

Trends in cancer - 1 Apr 2024

Papavassiliou Kostas A, Adamopoulos Christos, Papavassiliou Athanasios G

Abstract excerpt

In a recent study published in Cancer Cell, Cords et al. employed multiplexed imaging mass cytometry to analyze cancer-associated fibroblast (CAF) heterogeneity in 1070 NSCLC patients. This work defined good and poor prognostic CAF phenotypes, the latter associated with metastasis and chemoresistance, as well as revealed that CAF spatial location correlates with immune cell infiltration and clinical outcome.

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Identifiers

PMID: 38395732
DOI: 10.1016/j.trecan.2024.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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