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Article

Identification and Characterization of Cancer-Associated Fibroblast Subpopulations in Lung Adenocarcinoma

18 Jul 2022

Abstract excerpt

Cancer-associated fibroblasts (CAFs) reside within the tumor microenvironment, facilitating cancer progression and metastasis via direct and indirect interactions with cancer cells and other stromal cell types. CAFs are composed of heterogeneous subpopulations of activated fibroblasts, including myofibroblastic, inflammatory, and immunosuppressive CAFs. In this study, we sought to identify subpopulations of CAFs...

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PMID: 35884546
DOI: 10.3390/cancers14143486

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