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Article

A Robust Closed-Tube Method for Resolving tp53M214K Genotypes.

Zebrafish - 1 Jun 2024

Silvius Katherine M, Kendall Genevieve C

Abstract excerpt

The tp53M214K zebrafish mutant is a versatile platform with which to model a diverse spectrum of human diseases. However, currently available genotyping methods for this mutant require lengthy hands-on processes such as restriction digests and outsourced Sanger sequencing. To address this deficiency, we leveraged high-resolution melting analysis technology in conjunction with a parallel, in-tandem wild-type...

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Identifiers

PMID: 38386541
DOI: 10.1089/zeb.2023.0030
PMCID: PMC11296207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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