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Article

Determining the effectiveness of High Resolution Melting analysis for SNP genotyping and mutation scanning at the TP53 locus.

BMC genetics - 17 Feb 2009

Garritano Sonia, Gemignani Federica, Voegele Catherine, Nguyen-Dumont Tú, Le Calvez-Kelm Florence, De Silva Deepika, Lesueur Fabienne, Landi Stefano, Tavtigian Sean V

Abstract excerpt

BACKGROUND: Together single nucleotide substitutions and small insertion/deletion variants are the most common form of sequence variation in the human gene pool.High-resolution SNP profile and/or haplotype analyses enable the identification of modest-risk susceptibility genes to common diseases, genes that may modulate responses to pharmaceutical agents, and SNPs that can affect either their expression or...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19222838
DOI: 10.1186/1471-2156-10-5
PMCID: PMC2648999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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