Article
A robust closed-tube method for resolving <i>tp53</i> <sup>M214K</sup> genotypes
2023-01-23
Abstract excerpt
The tp53 M214K zebrafish mutant developed by Berghmans et al 2005 1 is a versatile platform with which to model a diverse spectrum of human diseases. However, currently available genotyping methods for this mutant require lengthy processes such as restriction digests and outsourced Sanger sequencing. To address this deficiency, we leveraged high-resolution melting analysis (HRMA) technology in conjunction with a...
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Identifiers and source
- Literature Corpus work
- d73ef7c7-73ed-5935-af58-9a630a0e8d90
- DOI
- 10.1101/2023.01.20.524903